Archives: October 14 – 21, 2010


Internal Medicine Grand Rounds — NOW AVAILABLE

The Department of Medicine at East Carolina University held it’s weekly Internal Medicine Grand Rounds on October 8, 2010. Dr. Paul Bolin discussed the following topic:

Hypertension Revisited – 2010

You can see the presentation by clicking here.

Dr. Bolin will be taking your questions and comments.

*** Note: Only registered users can participate in the virtual discussion. Not a registered user but interested in becoming one? Click here to complete our quick registration form.


Monthly Nephrology Journal Club — OCTOBER 19

Join the Division of Nephrology and Hypertension for our monthly journal club. Dr. Reginald Obi will be presenting:

Angiotensin Receptor Blockade and the risk of Cancer

The article will be available on October 15 by clicking here.

*** Note: Only registered users can participate in the virtual discussion. Not a registered user but interested in becoming one? Click here to complete our quick registration form.


Quarterly Statistics — NOW AVAILABLE

Each calendar quarter we bring you new statistics to let you know how successful Nephrology On-Demand has become. This quarter, we present data illustrating the types of users accessing this website.

To date, Nephrology On-Demand has 181 registered users. See the graphs below to compare the our registered and total user groups.



Puzzle of the Week HYPERTENSION REVISITED – 2010

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Questions

Across

  • 1. In 1980, this iteration of the JNC criteria recommend 4 classes of antihypertensive therapies: 1) diuretics, 2) adrenergic inhibiting agents, 3) vasodilators, and 4) additional adrenergic inhibiting agents (Archives of Internal Medicine 1980, Volume 140, p. 1280)
  • 2. It was not until the 4th iteration of the JNC guidelines (1988) that this well-known class of anti-hypertensive drugs were added to the algorithm for treating essential hypertension (___-___) (Archives of Internal Medicine 1988, Volume 148, p. 1028)
  • 3. At one point in time (2005), this drug was the 4th most prescribed drug in the US. As of 2009, it is the 19th most prescribed drug
  • 4. Atenolol is thought to not exert a tremendous effect on the pathophysiology of essential hypertension because of it's inability to block synthesis of this hormone (American Journal of Hypertension 2010, Volume 23, pp. 1014)
  • 5. As of January 2010, there have been this number of iterations of the JNC guidelines for diagnosing and treating essential hypertension
  • 6. Acronym of the trial that showed a benefit in composite renal outcomes with intensive blood pressure control in patients with proteinuria (NEJM 2010, Volume 363, p. 918)
  • 7. In all iterations of the JNC criteria for hypertension, this is the first therapeutic option in treating ANY stage of hypertension (___-____)
  • 8. A meta-analysis in 2009 showed that when comparing atenolol to any other anti-hypertensive medication, a variety of outcomes are improved by the use of atenolol over the other medication (JACC 2009, Volume 53, p. 2101)
  • 9. One of the first class of medications used in the modern era to control hypertension (NEJM 1949 p. 173)
  • 10. In 1991, a J shaped association was shown between hypertension and this cardiovascular outcome (____-____) (JAMA 1991, Volume 265, p. 489)
  • 11. As early as 1940 there was little to no prevention of hypertension

Down

  • 12. According to the 7th iteration of the JNC criteria, this stage is defined as a systolic BP of 120-139 mmHg or diastolic BP of 80-89 mmHg and should only be treated with lifestyle modification.
  • 13. Franklin D. Roosevelt, who suffered from hypertension, especially diastolic hypertension, eventually died from this complication of high blood pressure (____-____)
  • 14. The acronym of the trial, currently underway at East Carolina University, that is comparing two drug treatment strategies: sBP < 140 mmHg or sBP < 120 mmHg using either thiazide and/or ACE-inhibitors/ARB's to assess MI, stroke, hospitalizations, heart failure, or cardiovascular death
  • 15. The first line of therapy for patients with stage 1 hypertension (sBP 140-159 or dBP 90-99) according to JNC-7 criteria
  • 16. The acronym for the randomized trial that showed no difference in composite cardiovascular outcomes in type 2 diabetic patients who received intense blood pressure control than

Top Times

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Abstract Submissions — UPDATED OCTOBER 7, 2010

Keep your eyes on Nephrology On-Demand for more information on the following meetings:

International Forum on Quality and Safety in Healthcare 2011 — Abstract Deadline September 24, 2010
NKF Spring Clinical Meeting 2011 — Abstract Deadline December 3, 2010
North American Society for Dialysis and Transplantation 2010 — Abstract Deadline May 28, 2010
Southern Society for Clinical Investigation 2011 – Young Investigators Forum (YIF) — Abstract deadline October 18, 2010
ACP Medical Student Abstract Competition 2011 — deadline expected to be early-December 2010
ACP Resident and Fellows Abstract Competition 2011 — expected deadline not yet announced; check back in August October 2010 for more information
ISN Abstract Competition 2011 — expected deadline not yet announced
American Transplant Congress 2011 — Abstract Deadline December 3, 2010
International Society of Blood Purification — Abstract Deadline July August 30, 2010
Evidence 2010 — Abstract Deadline August 6, 2010
American Federation of Medical Research: Southern Regional Meetings 2011 — Abstract Deadline October 15, 2010
American Federation of Medical Research: Western Regional Meetings 2011 — Abstract Deadline October 1, 2010
American Society of Hypertension 2011 — Abstract Deadline December 6, 2010
International CRRT Meeting 2011 — Abstract Deadline December 3, 2010


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