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Author Topic: Phenytoin and hyponatremic seizure
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Post Phenytoin and hyponatremic seizure
on: December 24, 2012, 14:24
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Does phenytoin have a special anti epileptic effect in patients with hyponatremia?

Thanks.

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Post Re: Phenytoin and hyponatremic seizure
on: December 24, 2012, 14:28
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Turns out that phenytoin actually suppresses pituitary release of ADH through a calcium-related mechanism. That's probably why phenytoin is a better anti epileptic agent in huponatremic seizure patients.

http://www.nature.com/jp/journal/v22/n3/full/7210657a.html

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