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Forum » General Nephrology » Glomerulonephritides » Treatment for primary FSGS

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Author	Topic: Treatment for primary FSGS

Tejas

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Posts: 23
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Treatment for primary FSGS on: January 17, 2013, 14:31
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How would you treat a patient with primary FSGS?

Tejas

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Posts: 23
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Re: Treatment for primary FSGS on: January 17, 2013, 14:33
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A number of physicians would use conservative therapy (ACEi and/or ARB + HTN control) to treat sub-nephrotic proteinuric primary FSGS. However, there seems to be a lot of better data to suggest that nephrotic-range proteinuric FSGS patients can have a > 50% chance of entering partial or complete remission with steroid monotherapy for 4-6 months.

However, if you are concerned about using steroids (say the patient is already obese or has brittle bone) you can move directly to CsA or MMF as the initial treatment option.

A great review can be found here:
http://jasn.asnjournals.org/content/23/11/1769.full.pdf+html

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