VoiceThread is an asynchronous, collaborative tool which allows users to create and share multimedia slide shows. Slide shows can be created in various formats. Some of the common formats are video only, slides and video and slides and audio. Documents, PDFs, images and other types of media can be imported for use in a VoiceThread.

Viewers of a slide show also have the option to comment on the show using text, audio or video. Like text-based discussion boards, comments are organized in a threaded fashion allowing users to reply to existing comments or to create new comment threads.

In addition to faculty use, VoiceThread also provides an assignments feature. The assignments feature allows faculty to require to require students to create, watch or comment on a VoiceThread.